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Paul Smith | Researchclopedia

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Paul Smith

University of Melbourne ORCID

50

Works

2,773

Citations

20

h-index

25

i10-index

Research Topics

Ubiquitin and proteasome pathways Cancer-related Molecular Pathways Protein Degradation and Inhibitors

Affiliations

AstraZeneca (United Kingdom)2012–2023

National Institutes of Health1987–1987

St. Vincent's Birmingham2009–2010

Austrian Institute of Technology2015–2015

Institute of Cancer Research1996–2009

Top Works

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

Diane Crighton,Simon Wilkinson,et al.

20061,342 citations

Epigenetics and DNA Methylation

Cancer, Hypoxia, and Metabolism

p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

Tim Crook,Louise Brooks,et al.

1998178 citations

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.

Paul J. Adam,Joanne Berry,et al.

2003115 citations

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions

Paul Smith,Susan Crossland,et al.

1999107 citations

Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter

Adèle Hannigan,Paul Smith,et al.

2010101 citations

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

Moses Moustakim,Thomas Christott,et al.

201891 citations

The role of E3 ubiquitin ligases in the development and progression of glioblastoma

Luke Humphreys,Paul Smith,et al.

202183 citations

Localization of magnetic interictal discharges in temporal lobe epilepsy

Douglas F. Rose,Susumu Satô,et al.

198776 citations

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer

R Shah,Paul Smith,et al.

200974 citations