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Vladimir B. Seplyarskiy | Researchclopedia

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Vladimir B. Seplyarskiy

Brigham and Women's Hospital ORCID

52

Works

1,732

Citations

20

h-index

25

i10-index

Research Topics

Cancer Genomics and Diagnostics Evolution and Genetic Dynamics DNA Repair Mechanisms

Affiliations

University of Geneva2016–2016

Inova Health System2018–2018

Brigham and Women's Hospital2017–2026

University Medical Center Groningen2018–2018

Harvard University2017–2026

Top Works

Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma

Ximena Bonilla,Laurent Parmentier,et al.

2016485 citations

Genomics and Chromatin Dynamics

Epigenetics and DNA Methylation

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

Vladimir B. Seplyarskiy,Ruslan Soldatov,et al.

2016183 citations

Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence

Jakob M. Goldmann,Vladimir B. Seplyarskiy,et al.

2018104 citations

Population sequencing data reveal a compendium of mutational processes in the human germ line

Vladimir B. Seplyarskiy,Ruslan Soldatov,et al.

202172 citations

The origin of human mutation in light of genomic data

Vladimir B. Seplyarskiy,Shamil Sunyaev

202162 citations

Extraordinary Genetic Diversity in a Wood Decay Mushroom

Maria Baranova,Maria D. Logacheva,et al.

201558 citations

A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription

Vladimir B. Seplyarskiy,Evan Koch,et al.

202350 citations

Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations

Vladimir B. Seplyarskiy,Evgeny E. Akkuratov,et al.

201849 citations

Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand

Maria Andrianova,Georgii A. Bazykin,et al.

201745 citations