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Shaomin Li | Researchclopedia

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Shaomin Li

Brigham and Women's Hospital ORCID

197

Works

14,798

Citations

43

h-index

95

i10-index

Research Topics

Neuroscience and Neuropharmacology Research Alzheimer's disease research and treatments Neuroinflammation and Neurodegeneration Mechanisms

Affiliations

Tongji University2021–2021

Tufts University2006–2009

Brigham and Women's Hospital2006–2025

Boston Children's Hospital2025–2025

Beth Israel Deaconess Medical Center2004–2007

Top Works

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar,Shaomin Li,et al.

20083,625 citations

Memory and Neural Mechanisms

RNA modifications and cancer

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong,Victoria F. Beja-Glasser,et al.

20163,253 citations

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

Shaomin Li,Soyon Hong,et al.

2009946 citations

Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

Shaomin Li,Ming Jin,et al.

2011649 citations

Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty

Shaomin Li,William K. Cullen,et al.

2003571 citations

Complement<i>C3</i>-Deficient Mice Fail to Display Age-Related Hippocampal Decline

Qiaoqiao Shi,Kenneth J. Colodner,et al.

2015373 citations

Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate

Ting Yang,Shaomin Li,et al.

2016341 citations

A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer’s brain

Shaomin Li,Dennis J. Selkoe

2020257 citations

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

Tao Yu,Zhongyou Li,et al.

2010236 citations