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Jean‐Jacques Lohmann | Researchclopedia

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Jean‐Jacques Lohmann

AstraZeneca (France)

10

Works

297

Citations

8

h-index

6

i10-index

Research Topics

PI3K/AKT/mTOR signaling in cancer Coordination Chemistry and Organometallics Protein Kinase Regulation and GTPase Signaling

Affiliations

Centre National de la Recherche Scientifique1977–1977

Board of the Swiss Federal Institutes of Technology1981–1981

ETH Zurich1981–1981

AstraZeneca (France)2012–2017

Institut de Chimie1977–1977

Top Works

Discovery of (<i>R</i>)-8-(1-(3,5-Difluorophenylamino)ethyl)-<i>N</i>,<i>N</i>-dimethyl-2-morpholino-4-oxo-4<i>H</i>-chromene-6-carboxamide (AZD8186): A Potent and Selective Inhibitor of PI3Kβ and PI3Kδ for the Treatment of PTEN-Deficient Cancers

Bernard Barlaam,Sabina Cosulich,et al.

201486 citations

Cell Adhesion Molecules Research

Catalytic Alkyne Reactions

Alkylation of the isoquinoline skeleton in the 1-position

Dieter Seebàch,Jean‐Jacques Lohmann,et al.

198382 citations

Cyclopropenes as Vinylcarbenoids:Intermolecular Carbene‐Addition Reactions of Sulfinyl‐ and Sulfonylcyclopropenes at Room Temperature

M. FRANCK‐NEUMANN,Jean‐Jacques Lohmann

197738 citations

Lithiated <i>N</i>‐pivaloyl‐tetrahydroisoquinoline—a Supernuclephile

Jean‐Jacques Lohmann,Dieter Seebàch,et al.

198133 citations

Cyclopropene als Vinylcarbenoide: intermolekulare Carben‐Additionsreaktionen von Sulfinyl‐ und Sulfonyl‐cyclopropenen bei Raumtemperatur

M. FRANCK‐NEUMANN,Jean‐Jacques Lohmann

197716 citations

Lithiiertes <i>N</i>‐Pivaloyl‐tetrahydroisochinolin – ein Supernucleophil

Jean‐Jacques Lohmann,Dieter Seebàch,et al.

198113 citations

Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 1

Bénédicte Delouvrié,Katherine Al-Kadhimi,et al.

20129 citations

Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 2

Bénédicte Delouvrié,Katherine Al-Kadhimi,et al.

20129 citations

Discovery of a series of 8-(2,3-dihydro-1,4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours

Bernard Barlaam,Sabina Cosulich,et al.

20167 citations