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K. Dane Wittrup | Researchclopedia

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K. Dane Wittrup

Moscow Institute of Thermal Technology ORCID

558

Works

23,028

Citations

78

h-index

200

i10-index

Research Topics

Monoclonal and Polyclonal Antibodies Research Immunotherapy and Immune Responses Veterinary Oncology Research

Affiliations

Pasadena City College1990–1990

California Institute of Technology1988–1990

Scripps Research Institute1999–1999

Lahey Hospital and Medical Center2010–2010

Fox Chase Cancer Center2023–2023

Top Works

Yeast surface display for screening combinatorial polypeptide libraries

Eric T. Boder,K. Dane Wittrup

19971,784 citations

Cancer Research and Treatments

Cancer Immunotherapy and Biomarkers

Isolating and engineering human antibodies using yeast surface display

Ginger Chao,Wai Leung Lau,et al.

2006943 citations

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

Eric T. Boder,Katarina S. Midelfort,et al.

2000687 citations

Biophysical properties of the clinical-stage antibody landscape

Tushar Jain,Tingwan Sun,et al.

2017606 citations

Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance

Greg M. Thurber,Michael M. Schmidt,et al.

2008597 citations

A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

Michael M. Schmidt,K. Dane Wittrup

2009565 citations

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

Kelly D. Moynihan,Cary F. Opel,et al.

2016530 citations

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

Michael J. Feldhaus,Robert W. Siegel,et al.

2003519 citations

Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor

Leyuan Ma,Tanmay Dichwalkar,et al.

2019419 citations