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T J Ley | Researchclopedia

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T J Ley

James S. McDonnell Foundation

16

Works

7,150

Citations

13

h-index

13

i10-index

Research Topics

Acute Myeloid Leukemia Research Epigenetics and DNA Methylation Hemoglobinopathies and Related Disorders

Affiliations

James S. McDonnell Foundation2016–2016

St. Louis Children's Hospital1993–1993

Mayo Clinic1993–1993

University of California, San Francisco1993–1993

Washington University in St. Louis1995–2016

Top Works

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

20135,094 citations

RNA Interference and Gene Delivery

Cancer Genomics and Diagnostics

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

Matthew J. Walter,Li Ding,et al.

2011530 citations

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers

David A. Russler‐Germain,David H. Spencer,et al.

2014455 citations

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia

Jeffery M. Klco,David H. Spencer,et al.

2014401 citations

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

Sujan Shresta,Debra M. MacIvor,et al.

1995208 citations

Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.

Anne Moon,T J Ley

1990111 citations

The Human Mast Cell Chymase Gene (CMA1): Mapping to the Cathepsin G/Granzyme Gene Cluster and Lineage-Restricted Expression

George H. Caughey,Thomas H. Schaumberg,et al.

199389 citations

Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice.

Jay L. Grisolano,G M Sclar,et al.

199462 citations

Structure and function of the murine β-globin locus control region 5′ HS-3

Bruce A. Hug,Anne Moon,et al.

199258 citations