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Martin Toal | Researchclopedia

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Martin Toal

18

Works

3,562

Citations

6

h-index

6

i10-index

Research Topics

Histone Deacetylase Inhibitors Research Protein Degradation and Inhibitors Peptidase Inhibition and Analysis

Affiliations

Biogen (United States)2005–2006

Royal Marsden NHS Foundation Trust2012–2012

Institute of Cancer Research2012–2012

GlaxoSmithKline (United Kingdom)2022–2022

Age UK2022–2022

Top Works

A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis

Chris H. Polman,Paul O’Connor,et al.

20063,312 citations

Epigenetics and DNA Methylation

Acute Myeloid Leukemia Research

A Phase I Pharmacokinetic and Pharmacodynamic Study of CHR-3996, an Oral Class I Selective Histone Deacetylase Inhibitor in Refractory Solid Tumors

Udai Banerji,Leni van Doorn,et al.

201278 citations

Eight-year immunogenicity and safety of interferon beta-1a-Avonex®treatment in patients with multiple sclerosis

Robert M. Herndon,Richard A. Rudick,et al.

200564 citations

A phase I first‐in‐human study with tefinostat – a monocyte/macrophage targeted histone deacetylase inhibitor – in patients with advanced haematological malignancies

Gert J. Ossenkoppele,Bob Löwenberg,et al.

201345 citations

Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study

Jörge E. Cortes,Eric J. Feldman,et al.

201345 citations

Angiotensin Converting Enzyme (ACE) Inhibitors in the Treatment of Heart Failure in General Practice in North Cumbria

Martin Toal,Robert D. Walker

200011 citations

Phase 1 and preclinical profiling of ESM‐HDAC391, a myeloid‐targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia

Rebecca C. Furze,Mária Judit Molnár,et al.

20224 citations

A fatal complication of clozapine - induced agranulocytosis

Brian G Mangan,Martin Toal

19943 citations

509 The OPAL Study: A Phase II Study to Evaluate the Efficacy, Safety and Tolerability of Tosedostat (CHR-2797) in Elderly Subjects with Treatment Refractory or Relapsed Acute Myeloid Leukemia

Jörge E. Cortes,Eric J. Feldman,et al.

20112 citations