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Dean Hickman | Researchclopedia

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Dean Hickman

79

Works

2,835

Citations

28

h-index

44

i10-index

Research Topics

Alzheimer's disease research and treatments Tuberculosis Research and Epidemiology Pharmacovigilance and Adverse Drug Reactions

Affiliations

Biogen (United States)2019–2019

Mansfield University1992–1994

Amgen (United States)2007–2024

University of Washington1995–1998

TB Alliance2024–2026

Top Works

Engineered human blood–brain barrier microfluidic model for vascular permeability analyses

Cynthia Hajal,Giovanni S. Offeddu,et al.

2022230 citations

Computational Drug Discovery Methods

Pneumonia and Respiratory Infections

Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.

Dean Hickman,Ji Ping Wang,et al.

1998223 citations

Discovery of<i>N</i>-(4-(3-Amino-1<i>H</i>-indazol-4-yl)phenyl)-<i>N</i>‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitor

Yujia Dai,Kresna Hartandi,et al.

2007184 citations

N-acetyltransferase polymorphism

Dean Hickman,Edith Sim

1991171 citations

Potent Inhibition of the Cytochrome P-450 3A-Mediated Human Liver Microsomal Metabolism of a Novel HIV Protease Inhibitor by Ritonavir: A Positive Drug-Drug Interaction

Gondi Kumar,J.C. Dykstra,et al.

1999166 citations

Expression of arylamine <i>N</i> -acetyltransferase in human intestine

Dean Hickman,J. Pope,et al.

1998141 citations

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng,Ted Judd,et al.

2011136 citations

An on-chip model of protein paracellular and transcellular permeability in the microcirculation

Giovanni S. Offeddu,Kristina Haase,et al.

2019112 citations

Chromosomal localization of human genes for arylamine <i>N</i>-acetyltransferase

Dean Hickman,Angela Risch,et al.

1994109 citations