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Karl S. Peggs | Researchclopedia

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Karl S. Peggs

422

Works

32,224

Citations

84

h-index

200

i10-index

Research Topics

CAR-T cell therapy research Hematopoietic Stem Cell Transplantation Immune Cell Function and Interaction

Affiliations

National Health Service2017–2023

University College Hospital2000–2025

Guy's Hospital2000–2000

Memorial Sloan Kettering Cancer Center2005–2010

University College London Hospitals NHS Foundation Trust2003–2025

Top Works

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

Daniel W. Lee,Bianca Santomasso,et al.

20183,235 citations

Cytomegalovirus and herpesvirus research

Lymphoma Diagnosis and Treatment

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Nicholas McGranahan,Andrew J.S. Furness,et al.

20163,058 citations

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Christopher Abbosh,Nicolai J. Birkbak,et al.

20171,849 citations

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

Tyler R. Simpson,Fubin Li,et al.

20131,433 citations

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

Karl S. Peggs,Sergio A. Quezada,et al.

2009944 citations

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

Waseem Qasim,Hong Zhan,et al.

2017876 citations

Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

Sergio A. Quezada,Tyler R. Simpson,et al.

2010868 citations

Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies

Laurent Poirot,Brian Philip,et al.

2015581 citations

Checkpoint Blockade in Cancer Immunotherapy

Alan J. Korman,Karl S. Peggs,et al.

2006564 citations