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Maria Orr | Researchclopedia

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Maria Orr

27

Works

2,369

Citations

13

h-index

14

i10-index

Research Topics

PARP inhibition in cancer therapy Cancer Genomics and Diagnostics BRCA gene mutations in cancer

Affiliations

AstraZeneca (United Kingdom)2009–2021

University of Aberdeen1996–1996

Royal Cornhill Hospital1996–1996

Royal Aberdeen Children's Hospital1996–1996

AstraZeneca (Brazil)2014–2014

Top Works

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

Jonathan A. Ledermann,Philipp Harter,et al.

20141,434 citations

Lung Cancer Treatments and Mutations

Ovarian cancer diagnosis and treatment

Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes

Darren Hodgson,Brian Dougherty,et al.

2018230 citations

A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples

Gillian Ellison,Emma Donald,et al.

2010152 citations

Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study

Ruth Board,Gillian Ellison,et al.

2009100 citations

Biological and clinical evidence for somatic mutations in <i>BRCA1</i> and <i>BRCA2</i> as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting

Brian Dougherty,Zhongwu Lai,et al.

201799 citations

Targeted therapies in colorectal cancer—an integrative view by PPPM

Suzanne Hagan,Maria Orr,et al.

201384 citations

Impact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer

Pasi A. Jänne,Ian C. P. Smith,et al.

201575 citations

Analytical Validation of BRAF Mutation Testing from Circulating Free DNA Using the Amplification Refractory Mutation Testing System

Kyaw Lwin Aung,Emma Donald,et al.

201452 citations

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer (SOC) and a BRCA mutation (BRCAm).

Jonathan A. Ledermann,Philipp Harter,et al.

201339 citations