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Stephen L. Lowe | Researchclopedia

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Stephen L. Lowe

Eli Lilly (United States)

105

Works

4,174

Citations

26

h-index

58

i10-index

Research Topics

Alzheimer's disease research and treatments Neuroscience and Neuropharmacology Research Cholinesterase and Neurodegenerative Diseases

Affiliations

University of Iowa1972–1972

Marks and Spencer (United Kingdom)1990–1990

Georgia College & State University1974–1974

National University of Singapore1996–2016

Queen Mary University of London1990–1990

Top Works

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

Sandeep T. Patil,Lu Zhang,et al.

20071,032 citations

Receptor Mechanisms and Signaling

Computational Drug Discovery Methods

Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor

Patrick C. May,Robert A. Dean,et al.

2011366 citations

The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans

Patrick C. May,Brian A. Willis,et al.

2015199 citations

Evidence of Glutamatergic Denervation and Possible Abnormal Metabolism in Alzheimer's Disease

Andrew Procter,Alan M. Palmer,et al.

1988197 citations

Topographical distribution of neurochemical changes in Alzheimer's disease

Andrew Procter,Stephen L. Lowe,et al.

1988136 citations

GAMMA-AMINOBUTYRIC ACID CONCENTRATION IN BRAIN TISSUE AT TWO STAGES OF ALZHEIMER'S DISEASE

Stephen L. Lowe,Paul T. Francis,et al.

1988132 citations

Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease

Stephen L. Lowe,Brian A. Willis,et al.

2021116 citations

Reduced Glycine Stimulation of [<sup>3</sup>H]MK‐801 Binding in Alzheimer's Disease

Andrew Procter,E. H. F. Wjong,et al.

1989115 citations

Donanemab (LY3002813) Phase 1b Study in Alzheimer's Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging

Stephen L. Lowe,Cynthia Evans,et al.

2021102 citations