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Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

20062,633 citationsJournal Articlebronze Open Access

Authors

Dos D. Sarbassov · Broad Institute

Siraj M. Ali · Broad Institute

Shomit Sengupta · Broad Institute

Joon-Ho Sheen · Broad Institute

Peggy P. Hsu · Broad Institute

Alex F. Bagley · Broad Institute

Andrew L. Markhard · Broad Institute

Topics & Keywords

PI3K/AKT/mTOR signaling in cancer Protein Kinase Regulation and GTPase Signaling Metabolism, Diabetes, and Cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cell

Volume 22, Issue 2, pp. 159-168

DOI: 10.1016/j.molcel.2006.03.029

Field-Weighted Citation Impact: 51.85

David M. Sabatini · Broad Institute

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB | Researchclopedia