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Dos D. Sarbassov | Researchclopedia

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Dos D. Sarbassov

Nazarbayev University ORCID

98

Works

20,043

Citations

30

h-index

41

i10-index

Research Topics

PI3K/AKT/mTOR signaling in cancer Protein Kinase Regulation and GTPase Signaling FOXO transcription factor regulation

Affiliations

Broad Institute2006–2010

The University of Texas MD Anderson Cancer Center2009–2020

Howard Hughes Medical Institute2010–2010

University of California, San Francisco2001–2001

South Eastern Europe Telecommunications Academy2024–2024

Top Works

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov,David A. Guertin,et al.

20056,148 citations

Ubiquitin and proteasome pathways

Metabolism, Diabetes, and Cancer

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim,Dos D. Sarbassov,et al.

20022,961 citations

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Dos D. Sarbassov,Siraj M. Ali,et al.

20042,647 citations

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov,Siraj M. Ali,et al.

20062,633 citations

Growing roles for the mTOR pathway

Dos D. Sarbassov,Siraj M. Ali,et al.

20051,547 citations

GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR

Do‐Hyung Kim,Dos D. Sarbassov,et al.

2003948 citations

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

Chia‐Hsin Chan,Chien‐Feng Li,et al.

2012461 citations

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

Zhihong Zeng,Dos D. Sarbassov,et al.

2006342 citations

Redox Regulation of the Nutrient-sensitive Raptor-mTOR Pathway and Complex

Dos D. Sarbassov,David M. Sabatini

2005245 citations