Tissue distribution of the human MDR3 P-glycoprotein.

1994150 citationsJournal Article

Authors

Jasper Smit · The Netherlands Cancer Institute

Alfred H. Schinkel

Abstract

The highest expression of the MDR3 Pgp was found in liver in the canalicular membranes of hepatocytes. This is in agreement with a role for MDR3 in the transport of phospholipid into bile.

Topics & Keywords

Drug Transport and Resistance Mechanisms Gastroesophageal reflux and treatments Pediatric Hepatobiliary Diseases and Treatments

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: PubMed

Volume 71, Issue 5, pp. 638-49

Field-Weighted Citation Impact: 3.22