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Jasper Smit | Researchclopedia

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Jasper Smit

The Netherlands Cancer Institute ORCID

22

Works

5,694

Citations

16

h-index

18

i10-index

Research Topics

Drug Transport and Resistance Mechanisms Pediatric Hepatobiliary Diseases and Treatments Pharmacological Effects and Toxicity Studies

Affiliations

Leiden University2021–2021

Université Paris Cité1996–1996

Leiden University Medical Center2019–2020

Academic Medical Center1995–1995

The Netherlands Cancer Institute1991–2025

Top Works

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel,Jasper Smit,et al.

19942,272 citations

Cancer Immunotherapy and Biomarkers

Radiomics and Machine Learning in Medical Imaging

Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Jasper Smit,Alfred H. Schinkel,et al.

19931,460 citations

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

G J Zaman,C. H. M. Versantvoort,et al.

1994314 citations

The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice

Alexander J. Smith,Johanna L.P.M. Timmermans-Hereijgers,et al.

1994278 citations

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Ronald P.J. Oude Elferink,R. Ottenhoff,et al.

1995223 citations

Multidrug resistance and the role of P-glycoprotein knockout mice

Alfred H. Schinkel,Carla A.A.M. Mol,et al.

1995196 citations

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

Piet Borst,Alfred H. Schinkel,et al.

1993171 citations

Growth during infancy and early childhood in relation to blood pressure and body fat measures at age 8-18 years of IVF children and spontaneously conceived controls born to subfertile parents

Manon Ceelen,Mirjam M. van Weissenbruch,et al.

2009162 citations

Tissue distribution of the human MDR3 P-glycoprotein.

Jasper Smit,Alfred H. Schinkel,et al.

1994150 citations