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Christopher J. Paddon | Researchclopedia

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Christopher J. Paddon

Amyris (United States)ORCID

37

Works

6,498

Citations

24

h-index

28

i10-index

Research Topics

Plant biochemistry and biosynthesis Bacterial Genetics and Biotechnology RNA and protein synthesis mechanisms

Affiliations

National Institutes of Health1985–1985

University of Hertfordshire1996–2000

National Institute of Diabetes and Digestive and Kidney Diseases1985–1989

Laboratory of Molecular Genetics1993–1993

National Institute of Child Health1989–1991

Top Works

High-level semi-synthetic production of the potent antimalarial artemisinin

Christopher J. Paddon,Patrick J. Westfall,et al.

20132,037 citations

Microbial Natural Products and Biosynthesis

Fungal and yeast genetics research

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Patrick J. Westfall,Douglas J. Pitera,et al.

2012716 citations

Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

Christopher J. Paddon,Jay D. Keasling

2014668 citations

Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

Douglas J. Pitera,Christopher J. Paddon,et al.

2006443 citations

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

Hiroko Tsuruta,Christopher J. Paddon,et al.

2009367 citations

De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology

Jurgen F. Nijkamp,Marcel van den Broek,et al.

2012300 citations

Global Transcriptional Response of <i>Bacillus subtilis</i> to Heat Shock

John D. Helmann,Ming‐Fang Wu,et al.

2001242 citations

The Global Transcriptional Response of<i>Bacillus subtilis</i>to Peroxide Stress Is Coordinated by Three Transcription Factors

John D. Helmann,Ming‐Fang Wu,et al.

2002232 citations

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

Dae‐Kyun Ro,Mario Ouellet,et al.

2008195 citations