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Frédéric H. Vaillancourt | Researchclopedia

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Frédéric H. Vaillancourt

C4 Therapeutics (United States)ORCID

77

Works

4,300

Citations

28

h-index

37

i10-index

Research Topics

Click Chemistry and Applications Metal-Catalyzed Oxygenation Mechanisms Estrogen and related hormone effects

Affiliations

Boston University2006–2006

Boehringer Ingelheim (Germany)2006–2006

Harvard University2004–2009

University of British Columbia2002–2005

Purdue University West Lafayette2003–2003

Top Works

Nature's Inventory of Halogenation Catalysts: Oxidative Strategies Predominate

Frédéric H. Vaillancourt,Ellen Yeh,et al.

2006541 citations

Microbial bioremediation and biosurfactants

Computational Drug Discovery Methods

The Ins and Outs of Ring-Cleaving Dioxygenases

Frédéric H. Vaillancourt,Jeffrey T. Bolin,et al.

2006430 citations

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

Leah C. Blasiak,Frédéric H. Vaillancourt,et al.

2006393 citations

SyrB2 in syringomycin E biosynthesis is a nonheme Fe <sup>II</sup> α-ketoglutarate- and O <sub>2</sub> -dependent halogenase

Frédéric H. Vaillancourt,Jun Yin,et al.

2005330 citations

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

Frédéric H. Vaillancourt,Ellen Yeh,et al.

2005319 citations

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

Megan L. Matthews,Courtney M. Krest,et al.

2009247 citations

Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis: Trichlorination of Leucine during Barbamide Biosynthesis

Danica P. Galonić,Frédéric H. Vaillancourt,et al.

2006189 citations

Generation of D Amino Acid Residues in Assembly of Arthrofactin by Dual Condensation/Epimerization Domains

Carl J. Balibar,Frédéric H. Vaillancourt,et al.

2005160 citations

Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication

Frédéric H. Vaillancourt,Louise Pilote,et al.

2009145 citations