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Senthil K. Muthuswamy | Researchclopedia

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Senthil K. Muthuswamy

Beth Israel Deaconess Medical Center ORCID

254

Works

14,155

Citations

54

h-index

92

i10-index

Research Topics

Cancer Cells and Metastasis Pancreatic and Hepatic Oncology Research Cancer Genomics and Diagnostics

Affiliations

Ontario Institute for Cancer Research2008–2016

National Institutes of Health2023–2024

Beth Israel Deaconess Medical Center2016–2025

University Health Network2012–2016

Howard Hughes Medical Institute2007–2009

Top Works

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Jayanta Debnath,Senthil K. Muthuswamy,et al.

20032,005 citations

Monoclonal and Polyclonal Antibodies Research

HER2/EGFR in Cancer Research

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

Jayanta Debnath,Kenna R. Mills,et al.

2002763 citations

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

Ling Huang,Audrey Holtzinger,et al.

2015739 citations

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

Senthil K. Muthuswamy,Dongmei Li,et al.

2001558 citations

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

Mauricio J. Reginato,Kenna R. Mills,et al.

2003557 citations

Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo.

Stacy L. Moulder,F. Michael Yakes,et al.

2001549 citations

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Shizhen Emily Wang,Archana Narasanna,et al.

2006467 citations

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

Olga Anczuków,Avi Z. Rosenberg,et al.

2012465 citations

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Lixing Zhan,Avi Z. Rosenberg,et al.

2008418 citations