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Christopher A. Lipinski | Researchclopedia

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Christopher A. Lipinski

137

Works

46,021

Citations

32

h-index

62

i10-index

Research Topics

Computational Drug Discovery Methods Chemical Synthesis and Analysis Pharmacogenetics and Drug Metabolism

Affiliations

California Institute of Technology1970–1970

Translational Genomics Research Institute2007–2009

Midwestern University2021–2021

Mayo Clinic1996–2016

St Christopher's Hospice2015–2015

Top Works

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

Christopher A. Lipinski,Franco Lombardo,et al.

200117,632 citations

Angiogenesis and VEGF in Cancer

Cell Adhesion Molecules Research

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski,Franco Lombardo,et al.

199711,051 citations

Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski

20045,929 citations

Drug-like properties and the causes of poor solubility and poor permeability

Christopher A. Lipinski

20003,667 citations

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski,Franco Lombardo,et al.

20123,591 citations

Navigating chemical space for biology and medicine

Christopher A. Lipinski,Andrew L. Hopkins

20041,015 citations

Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions

Christopher A. Lipinski

2016572 citations

Increased Fibroblast Growth Factor-Inducible 14 Expression Levels Promote Glioma Cell Invasion via Rac1 and Nuclear Factor-κB and Correlate with Poor Patient Outcome

Nhan L. Tran,Wendy S. McDonough,et al.

2006185 citations

Quantitative Structure−Activity Relationships among Macrolide Antibacterial Agents: In Vitro and in Vivo Potency against <i>Pasteurella multocida</i>

James W. McFarland,Cynthia M. Berger,et al.

1997155 citations