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Christopher J. Schofield | Researchclopedia

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Christopher J. Schofield

Mansfield University ORCID

1,305

Works

62,516

Citations

112

h-index

697

i10-index

Research Topics

Cancer, Hypoxia, and Metabolism Epigenetics and DNA Methylation Antibiotic Resistance in Bacteria

Affiliations

Australian National University2004–2004

Manchester Metropolitan University2019–2022

University of London1974–2012

Oxfam2014–2020

Texas Biomedical Research Institute2011–2011

Top Works

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola,David R. Mole,et al.

20015,474 citations

Metal-Catalyzed Oxygenation Mechanisms

Enzyme Structure and Function

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein,Jonathan Gleadle,et al.

20013,326 citations

Oxygen sensing by HIF hydroxylases

Christopher J. Schofield,Peter J. Ratcliffe

20042,024 citations

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken,Christophe A. Girard,et al.

20071,512 citations

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury,Kar Kheng Yeoh,et al.

20111,021 citations

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier,Chun‐wa Chung,et al.

2012940 citations

Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

Wai‐Ching Hon,Michael Wilson,et al.

2002736 citations

Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

Kirsty S. Hewitson,Luke A. McNeill,et al.

2002710 citations

Expanding chemical biology of 2-oxoglutarate oxygenases

Christoph Loenarz,Christopher J. Schofield

2008492 citations