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Leslie M. Thompson | Researchclopedia

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Leslie M. Thompson

Massachusetts Institute of Technology ORCID

256

Works

21,126

Citations

71

h-index

147

i10-index

Research Topics

Genetic Neurodegenerative Diseases Mitochondrial Function and Pathology Muscle Physiology and Disorders

Affiliations

University of North Carolina at Charlotte2020–2023

University of North Carolina at Chapel Hill2018–2018

Texas Tech University1965–1965

Cedars-Sinai Medical Center2022–2022

Brigham and Women's Hospital1989–1990

Top Works

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

Rita Shiang,Leslie M. Thompson,et al.

19941,322 citations

Amyotrophic Lateral Sclerosis Research

Ubiquitin and proteasome pathways

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

Joan S. Steffan,László Bodai,et al.

20011,228 citations

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan,Aleksey Kazantsev,et al.

20001,060 citations

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

Emma Hockly,Victoria M. Richon,et al.

2003838 citations

SUMO Modification of Huntingtin and Huntington's Disease Pathology

Joan S. Steffan,Namita Agrawal,et al.

2004706 citations

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

Aleksey Kazantsev,Leslie M. Thompson

2008702 citations

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3

Patricia L. Tavormina,Rita Shiang,et al.

1995605 citations

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown,Oscar G. Wilkins,et al.

2022486 citations

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Alexandra Keenan,Sherry L. Jenkins,et al.

2017437 citations