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Robert A. Saxton | Researchclopedia

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Robert A. Saxton

University of California, Berkeley ORCID

28

Works

13,050

Citations

13

h-index

16

i10-index

Research Topics

PI3K/AKT/mTOR signaling in cancer Polyamine Metabolism and Applications Ubiquitin and proteasome pathways

Affiliations

Broad Institute2014–2017

Howard Hughes Medical Institute2014–2022

Moscow Institute of Thermal Technology2017–2017

Allen Institute2014–2017

Center for Cancer Research2016–2016

Top Works

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton,David M. Sabatini

20177,271 citations

Cytokine Signaling Pathways and Interactions

Immune Response and Inflammation

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton,David M. Sabatini

20172,060 citations

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson,Lynne Chantranupong,et al.

20151,239 citations

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

Lynne Chantranupong,Sonia M. Scaria,et al.

2016780 citations

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

Lynne Chantranupong,Rachel L. Wolfson,et al.

2014448 citations

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

Robert A. Saxton,Kevin E. Knockenhauer,et al.

2015439 citations

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1

Robert A. Saxton,Lynne Chantranupong,et al.

2016327 citations

Emerging principles of cytokine pharmacology and therapeutics

Robert A. Saxton,Caleb R. Glassman,et al.

2022198 citations

Structure of the nutrient-sensing hub GATOR2

Max L. Valenstein,Kacper B. Rogala,et al.

202275 citations