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Christilyn Graff | Researchclopedia

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Christilyn Graff

14

Works

1,819

Citations

10

h-index

10

i10-index

Research Topics

Monoclonal and Polyclonal Antibodies Research Glycosylation and Glycoproteins Research HER2/EGFR in Cancer Research

Affiliations

Biogen (United States)2007–2011

Massachusetts Institute of Technology2003–2003

Top Works

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

Michael J. Feldhaus,Robert W. Siegel,et al.

2003519 citations

Growth Hormone and Insulin-like Growth Factors

Cell Adhesion Molecules Research

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

Sha Mi,Bing Hu,et al.

2007486 citations

Theoretical analysis of antibody targeting of tumor spheroids: importance of dosage for penetration, and affinity for retention.

Christilyn Graff,K. Dane Wittrup

2003209 citations

Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 C

Christilyn Graff,Kerry Chester,et al.

2004139 citations

Engineering Antibody Affinity by Yeast Surface Display

David W. Colby,Brenda Kellogg,et al.

2004137 citations

Improving the solubility of anti‐LINGO‐1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

R. Blake Pepinsky,Laura Silvian,et al.

2010102 citations

Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration

R. Blake Pepinsky,Zhaohui Shao,et al.

201190 citations

A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity

Jianying Dong,Arlene Sereno,et al.

201179 citations

Characterization of Inhibitory Anti-insulin-like Growth Factor Receptor Antibodies with Different Epitope Specificity and Ligand-blocking Properties

Adam Doern,Xianjun Cao,et al.

200926 citations