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Franklin Chung | Researchclopedia

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Franklin Chung

18

Works

1,553

Citations

7

h-index

7

i10-index

Research Topics

Mitochondrial Function and Pathology Cancer, Hypoxia, and Metabolism Metabolism and Genetic Disorders

Affiliations

Novartis (Switzerland)2017–2017

Novartis (United States)2013–2013

Novartis Institutes for BioMedical Research2017–2017

Massachusetts Institute of Technology2014–2014

Top Works

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald,Antoine de Weck,et al.

2017693 citations

Cancer Genomics and Diagnostics

Diet and metabolism studies

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

Huayang Liu,Javad Golji,et al.

2018358 citations

IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism

Alexandra Grassian,Seth J. Parker,et al.

2014286 citations

Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth

Jinyun Chen,Franklin Chung,et al.

201387 citations

Targeting <i>HSF1</i> sensitizes cancer cells to HSP90 inhibition

Yaoyu Chen,Jinyun Chen,et al.

201359 citations

The Novolactone Natural Product Disrupts the Allosteric Regulation of Hsp70

Amr Hassan,C.A. Kirby,et al.

201457 citations

Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma

Michael Visser,Julien P. N. Papillon,et al.

202412 citations

Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism

Alexandra Grassian,Seth J. Parker,et al.

20142 citations

Supplementary Figures 1 - 6 from IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism

Alexandra Grassian,Seth J. Parker,et al.

20230 citations