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Olaf van Tellingen | Researchclopedia

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Olaf van Tellingen

The Netherlands Cancer Institute ORCID

458

Works

20,909

Citations

72

h-index

184

i10-index

Research Topics

Drug Transport and Resistance Mechanisms Glioma Diagnosis and Treatment Cancer Treatment and Pharmacology

Affiliations

University of Pisa2013–2013

National Institutes of Health2004–2004

Harvard University2013–2013

Radboud University Nijmegen2010–2010

University of Groningen1997–1997

Top Works

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel,Jasper Smit,et al.

19942,272 citations

Cancer therapeutics and mechanisms

Pharmacological Effects and Toxicity Studies

Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

Olaf van Tellingen,Bahar Yetkin-Arik,et al.

20151,007 citations

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

Alfred H. Schinkel,Ulrich Mayer,et al.

1997938 citations

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom,Judith van Asperen,et al.

1997878 citations

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

John Allen,Arnold van Loevezijn,et al.

2002687 citations

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

Guido J.R. Zaman,J. Lankelma,et al.

1995500 citations

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

Baoxu Pang,Xiaohang Qiao,et al.

2013426 citations

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Johan W. Smit,Maarten T. Huisman,et al.

1999355 citations

The Effect of Bcrp1 (Abcg2) on the <i>In vivo</i> Pharmacokinetics and Brain Penetration of Imatinib Mesylate (Gleevec): Implications for the Use of Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors to Enable the Brain Penetration of Imatinib in Patients

Pauline Breedveld,Dick Pluim,et al.

2005349 citations