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Albert M. Maguire | Researchclopedia

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Albert M. Maguire

258

Works

20,012

Citations

65

h-index

141

i10-index

Research Topics

Retinal Development and Disorders Retinal Diseases and Treatments Virus-based gene therapy research

Affiliations

University of Vermont2003–2003

Massachusetts Eye and Ear Infirmary1986–1986

Children's Hospital of Philadelphia2008–2024

Harvard University1986–1986

Penn Presbyterian Medical Center1993–2024

Top Works

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire,Francesca Simonelli,et al.

20082,126 citations

Retinal and Optic Conditions

Glaucoma and retinal disorders

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial

Stephen R. Russell,Jean Bennett,et al.

20171,830 citations

Gene therapy restores vision in a canine model of childhood blindness

Gregory M. Acland,Geoffrey K. Aguirre,et al.

20011,189 citations

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Albert M. Maguire,Katherine A. High,et al.

2009852 citations

Gene Therapy for Leber's Congenital Amaurosis is Safe and Effective Through 1.5 Years After Vector Administration

Francesca Simonelli,Albert M. Maguire,et al.

2009551 citations

Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness

Gregory M. Acland,Geoffrey K. Aguirre,et al.

2005473 citations

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial

Jean Bennett,Jennifer Wellman,et al.

2016450 citations

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

Samuel J. Reich,Joshua Fosnot,et al.

2003439 citations

AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness

Jean Bennett,Manzar Ashtari,et al.

2012387 citations