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Nicholas E. Hoffman | Researchclopedia

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Nicholas E. Hoffman

Temple University

35

Works

3,385

Citations

24

h-index

28

i10-index

Research Topics

Mitochondrial Function and Pathology Ion channel regulation and function Cardiac electrophysiology and arrhythmias

Affiliations

Cincinnati Children's Hospital Medical Center2012–2014

Fox Chase Cancer Center2013–2016

Howard Hughes Medical Institute2014–2014

Temple University Health System2016–2016

The Centers2016–2016

Top Works

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

Karthik Mallilankaraman,Patrick J. Doonan,et al.

2012651 citations

Ion Channels and Receptors

MicroRNA in disease regulation

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

James V. Michael,Jeremy G. T. Wurtzel,et al.

2017264 citations

Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation

Xinyuan Li,Pu Fang,et al.

2016212 citations

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics

Dhanendra Tomar,Zhiwei Dong,et al.

2016203 citations

SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore

Santhanam Shanmughapriya,Sudarsan Rajan,et al.

2015198 citations

Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms

Jason M. Duran,Catherine A. Makarewich,et al.

2013170 citations

Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function

Leroy C. Joseph,Dimitra Kokkinaki,et al.

2017155 citations

SLC25A23 augments mitochondrial Ca<sup>2+</sup>uptake, interacts with MCU, and induces oxidative stress–mediated cell death

Nicholas E. Hoffman,Harish C. Chandramoorthy,et al.

2014145 citations

MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity

Nicholas E. Hoffman,Harish C. Chandramoorthy,et al.

2013136 citations